HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Difluoropyrrolidine hydrochloride → HCID 58002346, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Difluoropyrrolidine hydrochloride | HCID 24903482 | — |
| Reactant | 4-Nitrophenyl 3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-5-[4-(trifluoromethoxy)phenyl]piperidine-1-carboxylate | HCID 58002632 | — |
| Product | HCID 58002346 | HCID 58002346 | — |
Reaction Steps
100 mg (0.19 mmol) of the compound from Example 176A and 83 mg (0.58 mmol) of 3,3-difluoropyrrolidine hydrochloride were reacted according to the General Method 6. Yield: 44 mg (45% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-5f7897457d0a4dc186f3dc87e40d1559 |
| Source note | uspto-grants-2012_02 |