N'-Hydroxy-2-methylpropanimidamide → HCID 58002254, compound

HRID 1642965Notes

Reaction equation

HRID 1642965 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:14][N:13]([C:15]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[O:16])[CH2:12][CH:11]([C:23](O)=[O:24])[CH2:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8].O[N:27]=[C:28]([NH2:32])[CH:29]([CH3:31])[CH3:30]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:10][CH:11]([C:23]3[O:24][N:32]=[C:28]([CH:29]([CH3:31])[CH3:30])[N:27]=3)[CH2:12][N:13]([C:15]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[O:16])[CH2:14]2)[CH:5]=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 2794833N'-Hydroxy-2-methylpropanimidamideHCID 58002579HCID 58002579, compound

Product 1

HCID 58002254HCID 58002254, compound

Procedure

100 mg (0.29 mmol) of the compound from Example 130A and 46 mg (0.43 mmol) of N′-hydroxy-2-methylpropanimidamide were reacted according to the General Method 2. Yield: 107 mg (90% of theory)

Sources & evidence

ORD record
ord-1ed937e1e2c94e46bb74cbcb22a8f535
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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