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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1642970Generated: November 1, 2026

5-(4-Ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acid → HCID 58002305, compound

https://huagongshe.com/reaction/1642970

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acidHCID 58002641—
ReactantHCID 66755613HCID 66755613—
ProductHCID 58002305HCID 58002305—

Reaction Steps

80 mg (0.22 mmol) of 5-(4-ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acid (Example 59A) and 68 mg (0.33 mmol) of 1-hydroxy-3-(trifluoromethyl)benzenecarboximidamide were reacted according to the General Method 2. Yield: 75 mg (64% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-c6b60633733549afbc4ed9406c912b89
Source noteuspto-grants-2012_02