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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1642972Generated: October 31, 2026

2,4-Difluorobenzamidoxime → HCID 58002719, compound

https://huagongshe.com/reaction/1642972

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzamidoximeHCID 2823825—
Reactant5-(4-Ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acidHCID 58002641—
ProductHCID 58002719HCID 58002719—

Reaction Steps

80 mg (0.22 mmol) of 5-(4-ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acid (Example 59A) and 60 mg (0.33 mmol) of 2,4-difluoro-N′-hydroxybenzenecarboximidamide were reacted according to the General Method 2. Yield: 69 mg (60% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-ae1fd7c3bb364560a7660233b07e200e
Source noteuspto-grants-2012_02