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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1642973Generated: October 31, 2026

5-(4-Ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acid → HCID 58002510, compound

https://huagongshe.com/reaction/1642973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acidHCID 58002641—
ReactantHCID 66755174HCID 66755174—
ProductHCID 58002510HCID 58002510—

Reaction Steps

80 mg (0.22 mmol) of 5-(4-ethylphenyl)-1-[(4-hydroxypiperidin-1-yl)carbonyl]piperidine-3-carboxylic acid (Example 59A) and 70 mg (0.33 mmol) of 1-hydroxy-4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazole-3-carboximidamide were reacted according to the General Method 2. Yield: 37 mg (30% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-15829d186dd94263991093a17870e29f
Source noteuspto-grants-2012_02