Hydrochloric Acid → HCID 66755460, compound

Participants

Reaction Steps

0.4 ml (1.7 mmol) of a 4N solution of hydrogen chloride in dioxane was added to a solution of 100 mg (0.17 mmol) of the compound from Example 166 in 0.25 ml of dioxane. The reaction mixture was stirred at room temperature for 20 h. The mixture was concentrated under reduced pressure, again taken up in 0.25 ml of dioxane, and once more 0.4 ml (1.7 mmol) of a 4N solution of hydrogen chloride in dioxane was added. The reaction mixture was stirred at room temperature for 16 h. The mixture was then concentrated to dryness under reduced pressure and dried until the weight remained constant. Yield: 92 mg (100% of theory).

Provenance & Evidence