Hydrochloric Acid → HCID 66755542, compound

Participants

Reaction Steps

0.6 ml (2.3 mmol) of a 4N solution of hydrogen chloride in dioxane was added to a solution of 130 mg (0.230 mmol) of the compound from Example 85A in 0.25 ml of dioxane. The reaction mixture was stirred at room temperature for 20 h. The mixture was concentrated under reduced pressure, again taken up in 0.25 ml of dioxane, and once more 0.6 ml (2.3 mmol) of a 4N solution of hydrogen chloride in dioxane was added. The reaction mixture was stirred at room temperature for 16 h. The mixture was then concentrated to dryness under reduced pressure and dried until the weight remained constant. Yield: 115 mg (92% of theory).

Provenance & Evidence