HCID 2763396, compound → HCID 58002686, compound

HRID 1642983Notes

Reaction equation

HRID 1642983 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][N:13]([C:15]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[O:16])[CH2:12][CH:11]([C:23](O)=[O:24])[CH2:10]2)=[CH:5][CH:4]=1)[CH3:2].O[N:27]=[C:28]([NH2:34])[CH2:29][S:30]([CH3:33])(=[O:32])=[O:31]>>[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:10][CH:11]([C:23]3[O:24][N:34]=[C:28]([CH2:29][S:30]([CH3:33])(=[O:32])=[O:31])[N:27]=3)[CH2:12][N:13]([C:15]([N:17]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)=[O:16])[CH2:14]2)=[CH:5][CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 2763396HCID 2763396, compoundHCID 580022255-(4-Ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acid

Product 1

HCID 58002686HCID 58002686, compound

Procedure

60 mg (0.17 mmol) of the compound from Example 38A and 40 mg (0.26 mmol) of N′-hydroxy-2-(methylsulphonyl)ethanimidamide were reacted according to the General Method 2. Yield: 15 mg (18% of theory)

Sources & evidence

ORD record
ord-ee4ea10bd7a34e68b91827a773633f7e
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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