(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002376, compound

HRID 1642984Notes

Reaction equation

HRID 1642984 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:14][N:13]([C:15]([N:17]3[CH2:22][CH2:21][CH:20]([OH:23])[CH2:19][CH2:18]3)=[O:16])[CH2:12][CH:11]([C:24](O)=[O:25])[CH2:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8].O[N:28]=[C:29]([NH2:34])[CH2:30][CH2:31][O:32][CH3:33]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:10][CH:11]([C:24]3[O:25][N:34]=[C:29]([CH2:30][CH2:31][O:32][CH3:33])[N:28]=3)[CH2:12][N:13]([C:15]([N:17]3[CH2:18][CH2:19][CH:20]([OH:23])[CH2:21][CH2:22]3)=[O:16])[CH2:14]2)[CH:5]=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 4390391(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 58002307HCID 58002307, compound

Product 1

HCID 58002376HCID 58002376, compound

Procedure

200 mg (0.54 mmol) of the compound from Example 128A and 128 mg (0.81 mmol) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 2. Yield: 138 mg (56% of theory)

Sources & evidence

ORD record
ord-06a18b62a05c47cdb455d5038cc2b201
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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