HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → {3-(3,4-Dimethylphenyl)-5-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}(morpholin-4-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride | HCID 4390391 | — |
| Reactant | HCID 58002579 | HCID 58002579 | — |
| Product | {3-(3,4-Dimethylphenyl)-5-[3-(2-methoxyethyl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}(morpholin-4-yl)methanone | HCID 58002169 | — |
Reaction Steps
200 mg (0.58 mmol) of the compound from Example 130A and 136 mg (0.87 mmol) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 2. Yield: 98 mg (40% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-d097fbfa9ebb4d908f960754cce1a4a2 |
| Source note | uspto-grants-2012_02 |