(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002209, compound

HRID 1642986Notes

Reaction equation

HRID 1642986 reaction equation
[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([O:21][C:22]([F:25])([F:24])[F:23])[CH:16]=3)[CH2:12][CH:11]([C:26](O)=[O:27])[CH2:10]2)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.O[N:30]=[C:31]([NH2:36])[CH2:32][CH2:33][O:34][CH3:35]>>[CH3:35][O:34][CH2:33][CH2:32][C:31]1[N:36]=[C:26]([CH:11]2[CH2:12][CH:13]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([O:21][C:22]([F:25])([F:23])[F:24])[CH:16]=3)[CH2:14][N:9]([C:7]([N:1]3[CH2:2][CH2:3][O:4][CH2:5][CH2:6]3)=[O:8])[CH2:10]2)[O:27][N:30]=1

Participants

3

Reactant 2

HCID 4390391(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 58002741HCID 58002741, compound

Product 1

HCID 58002209HCID 58002209, compound

Procedure

200 mg (0.50 mmol) of the compound from Example 201A and 117 mg (0.75 mmol) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 2. Yield: 106 mg (44% of theory)

Sources & evidence

ORD record
ord-297ade728e5c4fa887038eaa02c0cc1a
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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