3-fluoro-N'-hydroxybenzene-1-carboximidamide → HCID 58002598, compound

HRID 1643004Notes

Reaction equation

HRID 1643004 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[CH2:16][N:15]([C:17]([N:19]3[CH2:24][CH2:23][O:22][CH2:21][CH2:20]3)=[O:18])[CH2:14][CH:13]([C:25]([OH:27])=O)[CH2:12]2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[F:28][C:29]1[CH:30]=[C:31]([C:35](=[N:37]O)[NH2:36])[CH:32]=[CH:33][CH:34]=1>>[F:28][C:29]1[CH:30]=[C:31]([C:35]2[N:37]=[C:25]([CH:13]3[CH2:12][CH:11]([C:8]4[CH:9]=[CH:10][C:5]([S:2]([CH3:1])(=[O:4])=[O:3])=[CH:6][CH:7]=4)[CH2:16][N:15]([C:17]([N:19]4[CH2:20][CH2:21][O:22][CH2:23][CH2:24]4)=[O:18])[CH2:14]3)[O:27][N:36]=2)[CH:32]=[CH:33][CH:34]=1

Participants

3

Reactant 2

HCID 40909723-fluoro-N'-hydroxybenzene-1-carboximidamideHCID 58002581HCID 58002581, compound

Product 1

HCID 58002598HCID 58002598, compound

Procedure

60 mg (0.151 mmol) of the compound from Example 198A and 35 mg (0.227 mmol) of 3-fluoro-N′-hydroxybenzenecarboximidamide were reacted according to the General Method 2. Yield: 54 mg (67% of theory)

Sources & evidence

ORD record
ord-558d446171d34ae5a31ed44702dba7d9
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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