N'-Hydroxy-2-methylpropanimidamide → HCID 58002215, compound

HRID 1643019Notes

Reaction equation

HRID 1643019 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:14][N:13]([C:15]([N:17]3[CH2:20][CH:19]([OH:21])[CH2:18]3)=[O:16])[CH2:12][CH:11]([C:22](O)=[O:23])[CH2:10]2)[CH:5]=[CH:6][C:7]=1[CH3:8].O[N:26]=[C:27]([NH2:31])[CH:28]([CH3:30])[CH3:29]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:10][CH:11]([C:22]3[O:23][N:31]=[C:27]([CH:28]([CH3:30])[CH3:29])[N:26]=3)[CH2:12][N:13]([C:15]([N:17]3[CH2:20][CH:19]([OH:21])[CH2:18]3)=[O:16])[CH2:14]2)[CH:5]=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 2794833N'-Hydroxy-2-methylpropanimidamideHCID 58002370HCID 58002370, compound

Product 1

HCID 58002215HCID 58002215, compound

Procedure

72 mg (0.22 mmol) of the compound from Example 134A and 43 mg (0.33 mmol) of N′-hydroxy-2-methylpropanimidamide were reacted according to the General Method 2. Yield: 17 mg (19% of theory)

Sources & evidence

ORD record
ord-e5cb0a1b89ad4ccd8df2847e76c52749
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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