HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid → HCID 58002292, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid | HCID 58002500 | — |
| Reactant | HCID 136275400 | HCID 136275400 | — |
| Product | HCID 58002292 | HCID 58002292 | — |
Reaction Steps
150 mg (0.20 mmol) of 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid (Example 44A) and 80 mg (0.56 mmol) of N′-hydroxy-5-methylisoxazole-3-carboximidamide were reacted according to the General Method 2. Yield: 101 mg (54% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-b57bccbc28a4435886aaf797403f0b4d |
| Source note | uspto-grants-2012_02 |