HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002221, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride | HCID 4390391 | — |
| Reactant | 1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid | HCID 58002500 | — |
| Product | HCID 58002221 | HCID 58002221 | — |
Reaction Steps
150 mg (0.20 mmol) of 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid (Example 44A) and 66 mg (0.56 mmol) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 2. Yield: 77 mg (42% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-545434e67e874341ad9dd00d25c5e0dc |
| Source note | uspto-grants-2012_02 |