HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-n-hydroxybenzimidamide → HCID 58002679, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-n-hydroxybenzimidamide | HCID 593000 | — |
| Reactant | 1-[(4-Hydroxypiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid | HCID 58002340 | — |
| Product | HCID 58002679 | HCID 58002679 | — |
Reaction Steps
100 mg (0.250 mmol) of 1-[(4-hydroxypiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 99A) and 42.3 (0.275 mmol) of 4-fluoro-N′-hydroxybenzenecarboximidamide were reacted according to the General Method 1. Yield: 59.1 mg (46% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-99eb047db42b42adb4334d3e12364c0f |
| Source note | uspto-grants-2012_02 |