HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxyacetamidine → HCID 58002629, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxyacetamidine | HCID 30926 | — |
| Reactant | 1-[(4-Cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid | HCID 58002332 | — |
| Product | HCID 58002629 | HCID 58002629 | — |
Reaction Steps
100 mg (0.244 mmol) of 1-[(4-cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 100A) and 19.9 mg (0.269 mmol) of N′-hydroxyethanimidamide were reacted according to the General Method 1. Yield: 55.5 mg (47% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-f2db9d96b5844b159687ba030aa40842 |
| Source note | uspto-grants-2012_02 |