HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxynicotinimidamide → HCID 58002464, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxynicotinimidamide | HCID 308113 | — |
| Reactant | 1-[(4-Cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid | HCID 58002332 | — |
| Product | HCID 58002464 | HCID 58002464 | — |
Reaction Steps
100 mg (0.244 mmol) of 1-[(4-cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 100A) and 36.8 mg (0.269 mmol) of N′-hydroxypyridine-3-carboximidamide were reacted according to the General Method 1. Yield: 58.6 mg (46% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-e37bf41cf4d246b3a894fad0dd382fe5 |
| Source note | uspto-grants-2012_02 |