HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluorobenzamidoxime → HCID 58002680, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluorobenzamidoxime | HCID 2823825 | — |
| Reactant | 1-[(4-Cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid | HCID 58002332 | — |
| Product | HCID 58002680 | HCID 58002680 | — |
Reaction Steps
100 mg (0.244 mmol) of 1-[(4-cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 100A) and 46.2 mg (0.269 mmol) of 2,4-difluoro-N′-hydroxybenzenecarboximidamide were reacted according to the General Method 1. Yield: 63.9 mg (47% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-95c6a28525db4036b7d6a64984e84bb0 |
| Source note | uspto-grants-2012_02 |