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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643067Generated: November 1, 2026

3-Chlorobenzamidoxime → HCID 58002438, compound

https://huagongshe.com/reaction/1643067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-ChlorobenzamidoximeHCID 2794817—
Reactant1-[(4-Cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acidHCID 58002332—
ProductHCID 58002438HCID 58002438—

Reaction Steps

100 mg (0.244 mmol) of 1-[(4-cyanopiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 100A) and 45.8 mg (0.269 mmol) of 3-chloro-N′-hydroxybenzenecarboximidamide were reacted according to the General Method 1. Yield: 73.3 mg (55% of theory).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-e0c47b34f9424e6ea343113165891cdb
Source noteuspto-grants-2012_02