HuagongsheHuagongshe Chemistry Print Report · For research reference only
N'-hydroxy-2-phenylethanimidamide → HCID 58002621, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N'-hydroxy-2-phenylethanimidamide | HCID 2731007 | — |
| Reactant | 1-[(3-Hydroxyazetidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid | HCID 58002578 | — |
| Product | HCID 58002621 | HCID 58002621 | — |
Reaction Steps
100 mg (0.269 mmol) of 1-[(3-hydroxyazetidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 101A) and 44.4 mg (0.295 mmol) of N′-hydroxy-2-phenylethanimidamide were reacted according to the General Method 1. Yield: 40.0 mg (29% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-bdfeb866d42948e6a1bae2679deb85c4 |
| Source note | uspto-grants-2012_02 |