HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[(3-Hydroxyazetidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid → HCID 58002466, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[(3-Hydroxyazetidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid | HCID 58002578 | — |
| Reactant | HCID 136395912 | HCID 136395912 | — |
| Product | HCID 58002466 | HCID 58002466 | — |
Reaction Steps
90.0 mg (0.242 mmol) of 1-[(3-hydroxyazetidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 101A) and 61.0 mg (0.266 mmol) of 3,5-difluoro-N′-hydroxypyridine-2-carboximidamide were reacted according to the General Method 1. Yield: 24 mg (19% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-c67d217444244a159a1dc5331956b0d2 |
| Source note | uspto-grants-2012_02 |