15485-97-9 → HCID 58002406, compound

HRID 1643093Notes

Reaction equation

HRID 1643093 reaction equation
[C:1]([CH:3]1[CH2:8][CH2:7][N:6]([C:9]([N:11]2[CH2:16][CH:15]([C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([C:23]([F:26])([F:25])[F:24])[CH:18]=3)[CH2:14][CH:13]([C:27]([OH:29])=O)[CH2:12]2)=[O:10])[CH2:5][CH2:4]1)#[N:2].O[N:31]=[C:32]([NH2:37])[C:33]([OH:36])([CH3:35])[CH3:34]>>[OH:36][C:33]([C:32]1[N:37]=[C:27]([CH:13]2[CH2:14][CH:15]([C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([C:23]([F:25])([F:24])[F:26])[CH:18]=3)[CH2:16][N:11]([C:9]([N:6]3[CH2:5][CH2:4][CH:3]([C:1]#[N:2])[CH2:8][CH2:7]3)=[O:10])[CH2:12]2)[O:29][N:31]=1)([CH3:35])[CH3:34]

Participants

3

Reactant 2

HCID 507191215485-97-9HCID 58002152HCID 58002152, compound

Product 1

HCID 58002406HCID 58002406, compound

Procedure

100 mg (0.24 mmol) of the compound from Example 152A and 45 mg (0.37 mmol) of the compound from Example 77A were reacted according to the General Method 2. Yield: 45 mg (35% of theory)

Sources & evidence

ORD record
ord-c59e4a3f87bb4357bb98d4b3464c9fb2
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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