HCID 2763396, compound → HCID 58002469, compound

HRID 1643098Notes

Reaction equation

HRID 1643098 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][N:12]([C:14]([N:16]3[CH2:21][CH2:20][O:19][CH2:18][CH2:17]3)=[O:15])[CH2:11][CH:10]([C:22]([OH:24])=O)[CH2:9]2)=[CH:4][C:3]=1[C:25]([F:28])([F:27])[F:26].O[N:30]=[C:31]([NH2:37])[CH2:32][S:33]([CH3:36])(=[O:35])=[O:34]>>[CH3:36][S:33]([CH2:32][C:31]1[N:37]=[C:22]([CH:10]2[CH2:9][CH:8]([C:5]3[CH:6]=[CH:7][C:2]([CH3:1])=[C:3]([C:25]([F:28])([F:27])[F:26])[CH:4]=3)[CH2:13][N:12]([C:14]([N:16]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)=[O:15])[CH2:11]2)[O:24][N:30]=1)(=[O:35])=[O:34]

Participants

3

Reactant 2

HCID 2763396HCID 2763396, compoundHCID 58002297HCID 58002297, compound

Product 1

HCID 58002469HCID 58002469, compound

Procedure

100 mg (0.23 mmol) of the compound from Example 160A and 53 mg (0.35 mmol) of N′-hydroxy-2-(methylsulphonyl)ethanimidamide were reacted according to the General Method 2. Yield: 65 mg (54% of theory)

Sources & evidence

ORD record
ord-37032af9a8df4c9abbd80c79c0bc7717
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

Loading…