HCID 2763396, compound → HCID 58002508, compound

HRID 1643099Notes

Reaction equation

HRID 1643099 reaction equation
[OH:1][CH:2]1[CH2:7][CH2:6][N:5]([C:8]([N:10]2[CH2:15][CH:14]([C:16]3[CH:21]=[CH:20][C:19]([CH3:22])=[C:18]([C:23]([F:26])([F:25])[F:24])[CH:17]=3)[CH2:13][CH:12]([C:27]([OH:29])=O)[CH2:11]2)=[O:9])[CH2:4][CH2:3]1.O[N:31]=[C:32]([NH2:38])[CH2:33][S:34]([CH3:37])(=[O:36])=[O:35]>>[OH:1][CH:2]1[CH2:7][CH2:6][N:5]([C:8]([N:10]2[CH2:15][CH:14]([C:16]3[CH:21]=[CH:20][C:19]([CH3:22])=[C:18]([C:23]([F:24])([F:26])[F:25])[CH:17]=3)[CH2:13][CH:12]([C:27]3[O:29][N:38]=[C:32]([CH2:33][S:34]([CH3:37])(=[O:36])=[O:35])[N:31]=3)[CH2:11]2)=[O:9])[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 2763396HCID 2763396, compoundHCID 58002260HCID 58002260, compound

Product 1

HCID 58002508HCID 58002508, compound

Procedure

100 mg (0.24 mmol) of the compound from Example 163A and 55 mg (0.36 mmol) of N′-hydroxy -2-(methylsulphonyl)ethanimidamide were reacted according to the General Method 2. Yield: 72 mg (56% of theory)

Sources & evidence

ORD record
ord-d8bc7f7a54fb44d989928779a3b56332
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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