N'-Hydroxy-2-methylpropanimidamide → HCID 58002442, compound

HRID 1643101Notes

Reaction equation

HRID 1643101 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:13]2[CH2:18][N:17]([C:19]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)=[O:20])[CH2:16][CH:15]([C:27](O)=[O:28])[CH2:14]2)[CH:5]=[CH:6][C:7]=1[O:8][C:9]([F:12])([F:11])[F:10].O[N:31]=[C:32]([NH2:36])[CH:33]([CH3:35])[CH3:34]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:13]2[CH2:14][CH:15]([C:27]3[O:28][N:36]=[C:32]([CH:33]([CH3:35])[CH3:34])[N:31]=3)[CH2:16][N:17]([C:19]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)=[O:20])[CH2:18]2)[CH:5]=[CH:6][C:7]=1[O:8][C:9]([F:11])([F:10])[F:12]

Participants

3

Reactant 2

HCID 2794833N'-Hydroxy-2-methylpropanimidamideHCID 58002462HCID 58002462, compound

Product 1

HCID 58002442HCID 58002442, compound

Procedure

500 mg (1.15 mmol) of the compound from Example 167A and 130 mg (1.27 mmol) of N′-hydroxy-2-methylpropanimidamide were reacted according to the General Method 1. Yield: 286 mg (51% of theory)

Sources & evidence

ORD record
ord-c2d3d23eb46f4b5ca04d3be300981b91
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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