Ethyl 2-amino-2-(hydroxyimino)acetate → HCID 58002572, compound

HRID 1643116Notes

Reaction equation

HRID 1643116 reaction equation
[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=3)[CH2:12][CH:11]([C:25]([OH:27])=O)[CH2:10]2)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[NH2:28][C:29](=[N:35]O)[C:30]([O:32][CH2:33][CH3:34])=[O:31]>>[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:16]=[CH:17][C:18]([C:21]([F:22])([F:24])[F:23])=[CH:19][CH:20]=3)[CH2:12][CH:11]([C:25]3[O:27][N:35]=[C:29]([C:30]([O:32][CH2:33][CH3:34])=[O:31])[N:28]=3)[CH2:10]2)=[O:8])[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 6785548Ethyl 2-amino-2-(hydroxyimino)acetateHCID 580024471-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid

Product 1

HCID 58002572HCID 58002572, compound

Procedure

200 mg (about 0.47 mmol) of the compound from Example 49A and 54 mg (0.41 mmol) of ethyl amino(hydroximino)ethanoate were reacted according to the General Method 1. Yield: 17 mg (8% of theory).

Sources & evidence

ORD record
ord-815875f58acd4151b33b4ac0ddb119fe
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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