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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643117Generated: November 3, 2026

(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002401, compound

https://huagongshe.com/reaction/1643117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 4390391—
Reactant1-[(4-Hydroxypiperidin-1-yl)carbonyl]-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acidHCID 58002415—
ProductHCID 58002401HCID 58002401—

Reaction Steps

200 mg (about 0.432 mmol) of the compound from Example 63A and 102 mg (0.865 mmol) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 2. Yield: 92 mg (36% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-4158a7021d3e464da098ad7e5bc0ffd2
Source noteuspto-grants-2012_02