Hydrochloric Acid → HCID 66755474, compound

Participants

Reaction Steps

0.30 ml (1.16 mmol) of a 4N solution of hydrogen chloride in dioxane was added to a solution of 67 mg (0.117 mmol) of the compound from Example 92A in 0.6 ml of dioxane. The reaction mixture was stirred at room temperature for 20 hours. The mixture was concentrated using a rotary evaporator and once more taken up in 0.6 ml of dioxane, and 0.3 ml (1.16 mmol) of a 4N solution of hydrogen chloride in dioxane was added. The reaction mixture was stirred at room temperature overnight and then concentrated to dryness under reduced pressure and dried until the weight remained constant. Yield: 58 mg (100% of theory).

Provenance & Evidence