2-(Dimethylamino)acetohydrazide → HCID 58002364, compound

HRID 1643125Notes

Reaction equation

HRID 1643125 reaction equation
[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][C:18]([O:21][C:22]([F:25])([F:24])[F:23])=[CH:17][CH:16]=3)[CH2:12][CH:11]([C:26](O)=[O:27])[CH2:10]2)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:29][N:30]([CH3:36])[CH2:31][C:32]([NH:34][NH2:35])=O>>[CH3:29][N:30]([CH2:31][C:32]1[O:27][C:26]([CH:11]2[CH2:12][CH:13]([C:15]3[CH:16]=[CH:17][C:18]([O:21][C:22]([F:23])([F:24])[F:25])=[CH:19][CH:20]=3)[CH2:14][N:9]([C:7]([N:1]3[CH2:2][CH2:3][O:4][CH2:5][CH2:6]3)=[O:8])[CH2:10]2)=[N:35][N:34]=1)[CH3:36]

Participants

3

Reactant 2

HCID 683192-(Dimethylamino)acetohydrazideHCID 580025001-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid

Product 1

HCID 58002364HCID 58002364, compound

Procedure

100 mg (0.249 mmol) of the compound from Example 44A and 42 mg (0.275 mmol) of 2-(dimethylamino)acetohydrazide were reacted according to the General Method 4. Yield: 13 mg (11% of theory).

Sources & evidence

ORD record
ord-62ad7af089ee418b8f5aa770b18db485
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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