Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanethiol | HCID 6343 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | HCID 58002246 | HCID 58002246 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 58002423 | HCID 58002423 | — |
Reaction Steps
73 mg (0.221 mmol) of caesium carbonate and 36 μl (0.442 mmol) of ethanethiol were added to a solution of 100 mg (about 0.184 mmol) of the compound from Example 141A in 1.5 ml of dioxane. The reaction mixture was stirred at 70° C. for 4 hours. Without any further work-up, the mixture was purified by preparative HPLC. Yield: 40 mg (47% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08119663B2 |
|---|
| Source dataset | uspto-grants-2012_02 |
|---|
| ORD ID | ord-3f932abf2b7f40e0ba59933bcefd843e |
|---|
| Source note | uspto-grants-2012_02 |
|---|
