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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643148Generated: November 1, 2026

(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002604, compound

https://huagongshe.com/reaction/1643148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 4390391—
ReactantHCID 58002503HCID 58002503—
ProductHCID 58002604HCID 58002604—

Reaction Steps

250 mg (0.434 mmol, 72% pure) of 1-[(3-methoxypiperidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 207A) and 75.3 mg (0.478 mmol, 75% pure) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 1. Yield: 105 mg (48% of theory).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-ad51e3ca5719495290c70495a9d8c68a
Source noteuspto-grants-2012_02