Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643149Generated: October 31, 2026

(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002487, compound

https://huagongshe.com/reaction/1643149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 4390391—
ReactantHCID 58002437HCID 58002437—
ProductHCID 58002487HCID 58002487—

Reaction Steps

250 mg (0.626 mmol) of 1-[(3-oxopiperazin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]-piperidine-3-carboxylic acid (Example 206A) and 108 mg (0.689 mmol, 75% pure) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 1. Yield: 72.0 mg (23% of theory).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-7067412829994f1ea21b2c427151de32
Source noteuspto-grants-2012_02