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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643153Generated: November 1, 2026

(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002689, compound

https://huagongshe.com/reaction/1643153

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 4390391—
ReactantHCID 58002698HCID 58002698—
ProductHCID 58002689HCID 58002689—

Reaction Steps

250 mg (0.410 mmol, 68% pure) of 1-[(2,2-dimethylmorpholin-4-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 208A) and 71.1 mg (0.451 mmol, 75% pure) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 1. Yield: 103 mg (50% of theory).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-fe201582f3444c8a863bf78e73019462
Source noteuspto-grants-2012_02