HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58002698, compound → HCID 58002253, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58002698 | HCID 58002698 | — |
| Reactant | HCID 73010663 | HCID 73010663 | — |
| Product | HCID 58002253 | HCID 58002253 | — |
Reaction Steps
250 mg (0.410 mmol, 68% pure) of 1-[(2,2-dimethylmorpholin-4-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 208A) and 56.2 mg (0.451 mmol) of N′-hydroxypropanimidamide hydrochloride were reacted according to the General Method 1. Yield: 80.6 mg (42% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-659b85bfc7244b9b8f3417556c66d203 |
| Source note | uspto-grants-2012_02 |