(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 49820229, compound

HRID 1643156Notes

Reaction equation

HRID 1643156 reaction equation
[OH:1][CH:2]1[CH2:5][N:4]([C:6]([N:8]2[CH2:13][CH:12]([C:14]3[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=3)[CH2:11][CH:10]([C:25](O)=[O:26])[CH2:9]2)=[O:7])[CH2:3]1.O[N:29]=[C:30]([NH2:35])[CH2:31][CH2:32][O:33][CH3:34]>>[OH:1][CH:2]1[CH2:3][N:4]([C:6]([N:8]2[CH2:13][CH:12]([C:14]3[CH:19]=[CH:18][C:17]([O:20][C:21]([F:23])([F:22])[F:24])=[CH:16][CH:15]=3)[CH2:11][CH:10]([C:25]3[O:26][N:35]=[C:30]([CH2:31][CH2:32][O:33][CH3:34])[N:29]=3)[CH2:9]2)=[O:7])[CH2:5]1

Participants

3

Reactant 2

HCID 4390391(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 58002525HCID 58002525, compound

Product 1

HCID 49820229HCID 49820229, compound

Procedure

150 mg (0.324 mmol) of the compound from Example 110A and 77 mg (0.649 mmol) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 2. Yield: 23 mg (15% of theory).

Sources & evidence

ORD record
ord-c9c7a44e75a44c13aed0f9f7275096ee
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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