(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochloride → HCID 58002514, compound

HRID 1643167Notes

Reaction equation

HRID 1643167 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][NH:5][C:6]([N:8]1[CH2:13][CH:12]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=2)[CH2:11][CH:10]([C:24]([OH:26])=O)[CH2:9]1)=[O:7].O[N:28]=[C:29]([NH2:34])[CH2:30][CH2:31][O:32][CH3:33]>>[CH3:1][O:2][CH2:3][CH2:4][NH:5][C:6]([N:8]1[CH2:13][CH:12]([C:14]2[CH:15]=[CH:16][C:17]([C:20]([F:21])([F:22])[F:23])=[CH:18][CH:19]=2)[CH2:11][CH:10]([C:24]2[O:26][N:34]=[C:29]([CH2:30][CH2:31][O:32][CH3:33])[N:28]=2)[CH2:9]1)=[O:7]

Participants

3

Reactant 2

HCID 4390391(1E)-N'-Hydroxy-3-methoxypropanimidamide hydrochlorideHCID 58002436HCID 58002436, compound

Product 1

HCID 58002514HCID 58002514, compound

Procedure

100 mg (0.267 mmol) of the compound from Example 105A and 78 mg (0.497 mmol) of N′-hydroxy-3-methoxypropanimidamide were reacted according to the General Method 2. Yield: 22 mg (17% of theory)

Sources & evidence

ORD record
ord-810c7e5869cf4772808aa32358adeb0a
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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