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Bromine → 3-Bromo-1,1-dimethoxypropan-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | Pyruvic aldehyde dimethyl acetal | HCID 80650 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-Bromo-1,1-dimethoxypropan-2-one | HCID 12003567 | — |
反応手順
Bromine (80 g, 0.5 mol) is added dropwise to a solution of 1,1-dimethoxy-propan-2-one 205 (59 g, 0.5 mol) in anhydrous methanol (400 mL) at 0° C. and the solution is continued stirring at room temperature for 48h. The solvent is removed under reduced pressure and the residue is dried in vacuo and used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08119665B2 |
| 出典データセット | uspto-grants-2012_02 |
| ORD ID | ord-689142dd53324e63ae38e6e41a7fb966 |
| 出典メモ | uspto-grants-2012_02 |