Hydrochloric Acid → HCID 86639746, compound

Participants

Reaction Steps

To a solution of 2,6-di-t-butyl-4-mercaptophenol (2.00 g, 8.30 mmol) in methanol (10 mL) was added cyclobutanone (294 mg, 4.20 mmol) and a catalytic amount of concentrated hydrochloric acid. The mixture was heated under reflux for 6 hours. The solvent was distilled off from the mixture. The resulting residue was purified by a flash column chromatography to synthesize bis(3,5-di-t-butyl-4-hydroxyphenylthio)cyclobutane.

Provenance & Evidence