HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54718768, compound → HCID 66756882, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54718768 | HCID 54718768 | — |
| Reactant | HCID 66757266 | HCID 66757266 | — |
| Product | HCID 66756882 | HCID 66756882 | — |
Reaction Steps
Referring to Scheme 3, methoxybenzofuran ester 1, for example, is converted to the corresponding hydroxybenzofuran carboxylic acid 2 with boron tribromide. Carboxylic acid 2 is coupled with Hca amine to yield hydroxybenzofuranamide 3. 1-Substituted 4-hydroxypiperidine 4 is coupled with amide 3 to yield (piperidin-4-yloxy)benzofuranamide 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119809B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-e6a4608f2a294ddb815fe126126e7f36 |
| Source note | uspto-grants-2012_02 |