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HRID1643530

反应详情

EQUATION

反应方程式

HRID 1643530 的结构方程式

REACTANTS

反应物

1
结构：CC[C@@H](CO)NCCN[C@@H](CC)CO.Cl.Cl
HCID14051

Ethambutol dihydrochloride

C10H26Cl2N2O2

3 次

PRODUCTS

生成物

1
结构：CC[C@@H](CO)NCCN[C@@H](CC)CO
HCID14052

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O=C([O-])[O-].[Na+].[Na+]
溶剂HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：[Na+].[OH-]
溶剂HCID14798

Sodium Hydroxide

HNaO

PROCEDURE

实验过程

Ethambutol Dihydrochloride (ETB) is obtained from MP Biomedicals (Aurora, Ohio). ETB (7 grams) are dissolved in 100 mL of a saturated solution of sodium carbonate in 5M NaOH. The solution is stirred for 10 minutes and the free based ETB is extracted with three volumes of chloroform. The solution is dried over sodium sulfate. After filtration, the chloroform is removed by rotary evaporation. Ethambutol is represented in the structure below (a).

WORKUP

后处理

  1. extractionis extracted with three volumes of chloroform
  2. dry with materialThe solution is dried over sodium sulfate
  3. filtrationAfter filtration
  4. customthe chloroform is removed by rotary evaporation