Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Bromonicotinic acid → 6-Bromo-N,N-dimethylnicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Bromonicotinic acid | HCID 238932 | — |
| 반응물 | 5-bromo-N,N-dimethylpicolinamide | HCID 22831618 | — |
| 생성물 | 6-Bromo-N,N-dimethylnicotinamide | HCID 23092144 | — |
반응 단계
The title compound was prepared in a similar manner as described for Intermediate 161a, from 6-bromo-nicotinic acid (1.00 g, 4.95 mmol) to give a colorless oil (780 mg, 69% yield). 1H NMR (400 MHz, CDCl3) δ 8.46 (d, J=2.53 Hz, 1 H) 7.61-7.71 (m, 1 H) 7.56 (d, J=8.08 Hz, 1 H) 3.08 (d, J=41.68 Hz, 6 H); LCMS for C8H9BrN2O m/z 229.00 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08119624B2 |
| 출처 데이터셋 | uspto-grants-2012_02 |
| ORD ID | ord-4cb8de5523c047e98b5f81965ed54ba5 |
| 출처 메모 | uspto-grants-2012_02 |