HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 178480466, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 4-(6-Cyano-pyridin-3-yloxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide | HCID 66756100 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178480466 | HCID 178480466 | — |
Reaction Steps
To a solution of 4-(6-cyano-pyridin-3-yloxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide (181) in 3 mL EtOH was added 1 mL 50% NH4OH in water. The resulting mixture was stirred at room temperature for 2 hr, concentrated in vacuo, dried under vacuum, and used as it is for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119624B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-6973c2d4d76c4335b8436c255b94aabd |
| Source note | uspto-grants-2012_02 |