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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1644023Generated: October 26, 2026

1,3-Benzodioxole-5-carboxylic acid → (R)-N-(1-hydroxy-4-methylpentan-2-yl)benzo[d][1,3]dioxole-5-carboxamide

https://huagongshe.com/reaction/1644023

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole-5-carboxylic acidHCID 7196—
Reactant(R)-aminoleucinolHCID 86597565—
Product(R)-N-(1-hydroxy-4-methylpentan-2-yl)benzo[d][1,3]dioxole-5-carboxamideHCID 39364600—

Reaction Steps

Prepared in a similar manner to example 4 using benzo[d][1,3]dioxole-5-carboxylic acid and (R)-aminoleucinol. MS (M+H, 266.1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124121B2
Source datasetuspto-grants-2012_02
ORD IDord-711d890665574b668191cfb23a7a8f1b
Source noteuspto-grants-2012_02