huagongshe.com
HRID1644043

反应详情

EQUATION

反应方程式

HRID 1644043 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)[C@H](N)CC(C)C
HCID89967

(R)-Methyl 2-amino-4-methylpentanoate

C7H15NO2

结构：Cc1ccc2[nH]c(C(=O)O)cc2c1
HCID259188

5-Methyl-1H-indole-2-carboxylic acid

C10H9NO2

PRODUCTS

生成物

1
结构：COC(=O)[C@@H](CC(C)C)NC(=O)c1cc2cc(C)ccc2[nH]1
HCID7322438

未命名化合物

收率 50%

PROCEDURE

实验过程

Prepared in a similar manner to example 4 using 5-Methyl-1H-indole-2-carboxylic acid and D-leucine methyl ester. Yield: 50%. 1H NMR (500 MHz, CDCl3): 0.98 (d, 3H, J=6.3 Hz), 1.00 (d, 3H, J=6.1 Hz), 2.44 (s, 3H), 3.784 (s, 3H), 4.87 (m, 1H), 6.56 (d, 1H, J=8.39 Hz), 6.85 (dd, 1H, J=1.94 Hz, J=0.68 Hz), 7.12 (dd, 1H, J=8.46 Hz, J=1.55 Hz), 7.31 (d, 1H, J=8.45 Hz), 7.42 (s, 1H). MS (MH+, 303).