4-Fluorobenzaldehyde → 6-[(4-Fluorophenyl)hydroxymethyl]-1,2,3,4-tetrahydro-3-methyl-1-(1-methylethyl)-2,4-dioxo-thieno[2,3-d]pyrimidine-5-carboxylic acid ethyl ester

HRID 164405Notes

Reaction equation

HRID 164405 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][s:8][c:9]2[n:10]([CH:18]([CH3:19])[CH3:20])[c:11](=[O:17])[n:12]([CH3:16])[c:13](=[O:15])[c:14]12.[F:21][c:22]1[cH:23][cH:24][c:25]([CH:26]=[O:27])[cH:28][cH:29]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([CH:26]([c:25]2[cH:24][cH:23][c:22]([F:21])[cH:29][cH:28]2)[OH:27])[s:8][c:9]2[n:10]([CH:18]([CH3:19])[CH3:20])[c:11](=[O:17])[n:12]([CH3:16])[c:13](=[O:15])[c:14]12

Participants

3

Reactant 2

HCID 680234-FluorobenzaldehydeHCID 16102858Ethyl 1-isopropyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylate

Product 1

HCID 693110166-[(4-Fluorophenyl)hydroxymethyl]-1,2,3,4-tetrahydro-3-methyl-1-(1-methylethyl)-2,4-dioxo-thieno[2,3-d]pyrimidine-5-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-8c642a4c94ed4247a5d33186f7022fcc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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