HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1,1-Trimethoxy-2-chloroethane → Chloromethyl benzooxazol-5-carboxylic acid (1-propyl-butyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1,1-Trimethoxy-2-chloroethane | HCID 144702 | — |
| Reactant | 3-amino-4-hydroxy-N-(1-propylbutyl)benzamide | HCID 66773120 | — |
| Product | Chloromethyl benzooxazol-5-carboxylic acid (1-propyl-butyl)amide | HCID 57331139 | 65% |
Reaction Steps
Prepared in a similar manner to example 41 using 3-amino-4-hydroxy-N-(1-propylbutyl)benzamide (example 41a) and trimethyl chloro-orthoacetate. Yield: 65%. mp 108.5-109° C. MS (M+H, 309.05).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124121B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-0c09160e36784525bdfa0377b033bdf7 |
| Source note | uspto-grants-2012_02 |