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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1644062Generated: October 31, 2026

D-Leucine, methyl ester → (R)-methyl 2-(4-fluoro-3-methylbenzamido)-4-methylpentanoate

https://huagongshe.com/reaction/1644062

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-Leucine, methyl esterHCID 89967—
Reactant4-Fluoro-3-methylbenzoic acidHCID 242828—
Product(R)-methyl 2-(4-fluoro-3-methylbenzamido)-4-methylpentanoateHCID 57527876—

Reaction Steps

Prepared in a similar manner to example 4 using 4-fluoro-3-methylbenzoic acid and D-leucine methyl ester. MS (M+H, 282).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124121B2
Source datasetuspto-grants-2012_02
ORD IDord-04d6e8e8eb934bdaaf4b60c01d37f345
Source noteuspto-grants-2012_02