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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1644067Generated: October 26, 2026

3,4-Dimethylbenzoic acid → (R)-N-(1-hydroxy-4-methylpentan-2-yl)-3,4-dimethylbenzamide

https://huagongshe.com/reaction/1644067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Dimethylbenzoic acidHCID 12073—
Reactant(R)-aminoleucinolHCID 86597565—
Product(R)-N-(1-hydroxy-4-methylpentan-2-yl)-3,4-dimethylbenzamideHCID 3935241475%

Reaction Steps

(R)—N-(1-hydroxy-4-methylpentan-2-yl)-3,4-dimethylbenzamide was prepared in a similar manner as described in example 4 using 3,4-dimethylbenzoic acid and with (R)-aminoleucinol. Yield: 75%. MS (M+H, 250.3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124121B2
Source datasetuspto-grants-2012_02
ORD IDord-e8be55fdd47c4db885a355a3bea527d2
Source noteuspto-grants-2012_02