4-Heptanamine → 2-chloro-N-(heptan-4-yl)-6-methylnicotinamide

HRID 1644085Notes

Reaction equation

HRID 1644085 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]([CH3:11])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:12][CH2:13][CH2:14][CH:15]([NH2:19])[CH2:16][CH2:17][CH3:18]>>[Cl:1][C:2]1[N:10]=[C:9]([CH3:11])[CH:8]=[CH:7][C:3]=1[C:4]([NH:19][CH:15]([CH2:16][CH2:17][CH3:18])[CH2:14][CH2:13][CH3:12])=[O:6]

Participants

3

Reactant 2

HCID 386654-HeptanamineHCID 1217242-Chloro-6-methylnicotinic acid

Product 1

HCID 575278462-chloro-N-(heptan-4-yl)-6-methylnicotinamide

Procedure

Prepared in a similar manner to example 4 using 2-chloro-6-methylnicotinic acid and 4-Heptylamine. MS (M+H, 269).

Sources & evidence

ORD record
ord-1d66cdf20ac44f86bdd44c342bf1006d
Source dataset
uspto-grants-2012_02
Patent number
US08124121B2

Reaction notes

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